Question: Does PEP Have Long Term Side Effects?

What are the side effects of PEP?

PEP can cause side effects in some people, such as:tiredness.diarrhoea.nausea.vomiting.feeling generally unwell..

Does Pep lower your immune system?

Conclusions: The rates of activation and senescence of the immune system were significantly lower in CD4 T cells from individuals on PEP with TVD plus RAL as compared with those with the other two regimens.

What causes pep failure?

PEP failure, when it occurs, is usually attributed to delayed initiation, transmitted drug resistance, or suboptimal medication adherence.

How long does PEP last?

How Long Do I Need to Take PEP? If you are prescribed PEP, you will need to take the HIV medicines every day for 28 days. You will also need to return to your health care provider at certain times while taking PEP and after you finish taking it for HIV testing and other tests.

Does Pep make you sick?

If you are taking PEP you could experience some unpleasant side-effects such as feeling sick, being sick, diarrhoea, tiredness, and generally feeling unwell. The drugs used in a course of PEP today are less likely to cause side-effects than those used in the past.

How many times can you take PEP?

You take PEP 1-2 times a day for at least 28 days. The medicines used in PEP are called antiretroviral medications (ART). These medicines work by stopping HIV from spreading through your body.

Can I infect someone while on PEP?

No. Unsafe sex while taking PEP could let more HIV into your body, making PEP much more likely not to work. If after taking PEP someone’s stayed HIV negative and then has unsafe sex again, they can become infected just like any other HIV negative person.

What happens if you miss a day of pep?

Do not double a dose if you miss one. If you do miss a dose and you remember in less than 24 hours, take the missed dose as soon as you remember. If you miss more than 48 hours of PEP ( two consecutive doses ) it will be discontinued.

Can Pep cause liver damage?

In addition, three patients reported rash a median of ten days after the initiation of PEP, leading one patient to discontinue therapy. Two patients developed mild liver toxicities (grade 1 and grade 2) 14 and 28 days after starting PEP, and there were two instances of severe liver toxicity.

Does Pep cause weight loss?

The most common reported side-effects (over 1% of people) of lamivudine/zidovudine taken together are: nausea, vomiting, diarrhoea, tiredness, headache, dizziness, weakness, muscle pain, loss of appetite, fever, abdominal pain, hair loss, insomnia, rash, cough, runny nose, joint or muscle pain, fat loss, anaemia, low …

Can I drink alcohol while on PEP?

Do not drink alcohol while taking this medication. Women under the age of 20 should not take this medicine. Keep these medications out of the sight and reach of children.

What is the success rate of pep?

Adherence to a full 28-day course of ARVs is critical to the effectiveness of the intervention. Recent evidence shows PEP uptake has been insufficient: only 57% of the people who initiated PEP have completed the full course and rates were even lower at 40% for victims of sexual assault.

Can I take PEP for 30 days?

PEP is a short-term medical treatment: a 30-day long regimen, that can prevent the proliferation of the HIV virus in the body – an infection – following unprotected sex or other types of exposure to HIV.

Is Pep effective after 60 hours?

This, as highlighted above, has been demonstrated in animal models. Thus, even though PEP is often offered for up to 72 hours after exposure, it should be initiated as early as possible. After 72 hours, PEP is not effective, and there are gradations in efficacy from 24 hours postexposure, to 36, 48, and 72 hours.