Question: Does Pep Cause Liver Damage?

How bad are pep side effects?

The most common side-effects were fatigue (37% of PEP users), diarrhoea (25%), nausea (24%), flatulence (24%), abdominal cramps (21%), bloating (16%), headache (15%), vivid dreams (15%), depression (10%) and thirst (10%)..

Can you test positive while on PEP?

After a course of PEP you need to wait 28 days before testing for HIV. This is because PEP can delay infection.

What causes pep failure?

PEP failure, when it occurs, is usually attributed to delayed initiation, transmitted drug resistance, or suboptimal medication adherence.

What happens if you miss a day of pep?

If you do miss a dose and you remember in less than 24 hours, take the missed dose as soon as you remember. If you miss more than 48 hours of PEP ( two consecutive doses ) it will be discontinued.

Can I infect someone while on PEP?

No. Unsafe sex while taking PEP could let more HIV into your body, making PEP much more likely not to work. If after taking PEP someone’s stayed HIV negative and then has unsafe sex again, they can become infected just like any other HIV negative person.

What does Truvada do to your body?

Both medicines inside Truvada interfere with an enzyme called reverse transcriptase, which is used by HIV-infected cells to make new viruses. Since Truvada reduces the activity of reverse transcriptase, it causes HIV-infected cells to slow down or stop producing new viruses.

Does PEP have long term effects?

As with most antiretroviral drugs, PEP can cause side effects such as diarrhoea, headaches, nausea/vomiting and fatigue. However these are usually mild and generally only last a few days with no long-term side effects. Speak with your GP or sexual health clinic if you have any concerns.

How long must you take PEP?

You must start the treatment as soon as possible after you’ve been exposed to HIV, ideally within a few hours. The medicines must be taken every day for 28 days (4 weeks). PEP is unlikely to work if it’s started after 3 days (72 hours) and it won’t usually be prescribed after this time.

Can you drink alcohol on PEP?

You may drink moderate amounts of alcohol (within normal recommended safe limits) while taking this medication. If you usually take multivitamins, calcium tablets or treatment for indigestion, please discuss this with the Doctor or Nurse as they may affect how well the Raltegravir is absorbed.

Can you drink alcohol while on PEP treatment?

Do not drink alcohol while taking this medication. Women under the age of 20 should not take this medicine. Keep these medications out of the sight and reach of children.

Does Truvada weaken the immune system?

The antiretroviral (ARV) drug tenofovir (found in Viread, Truvada and Atripla) might calm the immune system in people with HIV and make them less susceptible to other infections, according to a study published online April 5 in the Journal of Acquired Immune Deficiency Syndromes.

Is Pep bad for your liver?

Results: The most frequent clinical side effect was fatigue (in 23 cases, 88.5%), and gastroenterological symptoms were the second most common side effects in HCP with PEP. Liver dysfunction was found in 10 cases (38.5%), while drug rash was found in 18 cases (69.2%) after PEP.

Can Truvada cause liver damage?

You may be more likely to get lactic acidosis or serious liver problems if you are female, very overweight (obese), or have been taking TRUVADA for a long time. In some cases, these serious conditions have led to death. Call your healthcare provider right away if you have any symptoms of these conditions.

Can I take PEP for 30 days?

Drugs used for PEP PEP should be taken for 28 days. It is important to take all the doses, at the right time and in the right way, to give PEP the best chance of working. You might be given an additional two days’ drugs if you have been at risk of exposure in the last 48 hours of the course of PEP.

Is Pep 100% effective?

PEP does not prevent 100% of HIV infections but it is very effective at preventing HIV if used consistently and correctly. Observational research suggests that PEP can reduce the risk of getting HIV by more than 80%, which means some people in the studies acquired HIV despite taking PEP.