Can Valtrex Cause Kidney Failure?

Is Valtrex nephrotoxic?

While valacyclovir is the antiviral agent used worldwide, it is reported to induce nephrotoxicity..

Do antivirals weaken your immune system?

Whereas AZT, ribavirin, or ganciclovir were antiproliferative, ddI or acyclovir had little, if any, effect on PBMC mitogenesis. The inhibitory effects of antivirals on immune cells may contribute to the immune deterioration observed in patients following prolonged use of the drugs.

How long can I stay on Valtrex?

Valacyclovir is usually prescribed for seven days for shingles, with a typical dosage of 1,000 mg three times per day. Just like with HSV-1 and HSV-2, it’s important to start treatment as soon as you notice shingles symptoms.

Does acyclovir work better than Valtrex?

(Acyclovir itself is available as a topical, oral, and intravenous medication.) Valtrex thus is active against the same viruses as acyclovir, but Valtrex has a longer duration of action than acyclovir and can be taken fewer times each day.

Does acyclovir weaken immune system?

This medication may rarely cause a life-threatening disorder that affects the blood cells, kidneys, and other parts of the body. This disorder is more likely to occur if you have conditions related to a weakened immune system (such as HIV disease, bone marrow transplant, kidney transplant).

Can you still have outbreaks while on Valtrex?

Can you have an outbreak while taking Valtrex? Yes, while daily Valtrex has been shown to reduce genital herpes outbreaks by 70% to 80%, it is still possible to have an outbreak while taking the medication. However, the frequency of outbreaks tends to go down over time for a lot of people.

Can acyclovir cause kidney problems?

Abstract. Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal function that develops within 24–48 hours of acyclovir administration indicated by a rapid rise in the serum creatinine.

What are the long term side effects of Valtrex?

Another potential long-term side effect of valacyclovir usage is HUS/TTP, or hemolytic-uremic syndrome and thrombotic thrombocytopenic purpura. These similar disorders can lead to the destruction of red blood cells and a low platelet count, preventing your blood’s ability to clot.

Can damage to kidneys be reversed?

Acute kidney failure can be fatal and requires intensive treatment. However, acute kidney failure may be reversible. If you’re otherwise in good health, you may recover normal or nearly normal kidney function.

Is it safe to take valacyclovir everyday?

To help clear up your infection, keep taking valacyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

Is taking Valtrex long term safe?

CHARLESTON, S.C. — Once-daily treatment with valacyclovir for the suppression of genital herpes caused by herpes simplex virus type 2 was well tolerated for up to 20 months in a recent study.

Can I drink alcohol while taking Valtrex?

There are no specific warnings about drinking alcohol while taking Valtrex, but you should speak with your doctor, and it may be best to avoid alcohol when using this treatment. If you drink alcohol while taking Valtrex, it can make the symptoms of the medication worse.

Does Valtrex damage kidneys?

For people with kidney problems: Your kidneys clear this drug from your body. If you have kidney problems or a history of kidney disease, you may not be able to clear it from your body. This may increase the levels of the drug in your body and cause more side effects. This drug can also make your kidney function worse.

Does taking Valtrex weaken your immune system?

However, because they suppress the immune system, these medicines also suppress the ability of the body to fight infection. Valaciclovir is therefore given to people who have received an organ transplant, in order to help the body kill off any CMV virus.

Does Valtrex make you pee a lot?

Drink extra fluids so you will pass more urine while you are using this medicine. This will keep your kidneys working well and help prevent kidney problems. To help clear up your infection, keep taking valacyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days.